How to Value Orphan Drugs? A Review of European Value Assessment Frameworks
نویسندگان
چکیده
منابع مشابه
Value-Based Reimbursement Decisions for Orphan Drugs: A Scoping Review and Decision Framework
BACKGROUND The rate of development of new orphan drugs continues to grow. As a result, reimbursing orphan drugs on an exceptional basis is increasingly difficult to sustain from a health system perspective. An understanding of the value that societies attach to providing orphan drugs at the expense of other health technologies is now recognised as an important input to policy debates. OBJECTI...
متن کاملPrinciples for consistent value assessment and sustainable funding of orphan drugs in Europe
The European Orphan Medicinal Products (OMP) Regulation has successfully encouraged research to develop treatments for rare diseases resulting in the authorisation of new OMPs in Europe. While decisions on OMP designation and marketing authorisation are made at the European Union level, reimbursement decisions are made at the national level. OMP value and affordability are high priority issues ...
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BACKGROUND Several organizations have developed frameworks to systematically assess the value of new drugs. OBJECTIVE To evaluate the convergent validity and interrater reliability of 4 value frameworks to understand the extent to which these tools can facilitate value-based treatment decisions in oncology. METHODS Eight panelists used the American Society of Clinical Oncology (ASCO), Europ...
متن کاملScientific and Social Value Judgments for Orphan Drugs in Health Technology Assessment.
OBJECTIVES We explore how broader aspects of a treatment's value and the impact of the condition on patients not captured by routine health technology assessment (HTA) methods using clinical and economic evidence, defined as "other considerations," may influence HTA processes in different settings. METHODS Countries included were England, Scotland, Sweden, and France. Data sources were the pu...
متن کاملValue-based argumentation frameworks
In this paper I introduce the notion of Value-Based Argumentation Frameworks (VAF). I start from a standard notion of argumentation frameworks which has been widely used to analyse logics for defeasible argument, and extend it so as to make defeat dependent on the relative importance of the values the arguments advance or protect. The idea is to re-introduce an element which has been abstracted...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: 1663-9812
DOI: 10.3389/fphar.2021.631527